It is in force if referenced in the QA program, and will depend on the whether a commitment to the governing Regulatory Authority exists to implement the N45.2 standard as described in the QA Program..
Please read Appendix A of Revision 4 to Regulatory Guide 1.28 issued 06/2010 by the NRC found at the link below:
http://adamswebsearch2.nrc.gov/idmws/Vi ... L100160003Keep this in mind.....The NRC withdrew several Regulatory Guides related to QA over the years. But. the withdrawal of a Regulatory Guide does not alter any prior or existing licensee commitments based on the use of a withdrawn Regulatory Guide. Licensees with prior or existing commitments to a withdrawn standard(s) may continue to implement those provisions or revise their commitments to adopt an acceptable version of the ASME NQA-1 standard